This machine is used to compact the powder sample into a tablet in the sampling die itself by hydraulic pressure. A 3,000 lb capacity pressure gauge is provided. No electricity or compressed air is required.
The machine is compact (8”D x 16”W x 16”H) and portable (30 lb) and works with standard tablet tooling. QAQC Lab offers, for the sake of customers’ convenience, six different types and sizes of standardized punches, covering the entire sample size range of 0.1cc to 3.0cc.
A table showing the sample size and corresponding punch type and size is given below:
“New Unit-Dose Powder Sampling Technique.”
• Manufactured from 316 stainless steel
• Satin polish (Ra< 1microns)
• Take Multiple Samples from the same Point
• Range of sampler lengths
• Change the sample volume by changing the insert
• Special finishes and materials of construction available on request.
Samples are taken from powder blends to test for content uniformity before further processing, such
as tableting or encapsulation. Integrity of the sampling technique is critical in order to ensure
accuracy of the test results. Unit-dose sampling has been proven to improve the accuracy of the
content uniformity results. However, there is still room for sampling error in unit-dose sampling
if the samples are submitted to the laboratory in powder form.
This New Unit-dose Powder Sampling Technique further reduces the sampling error by combining
unit-dose sampling with compaction of the powder sample into a real tablet in the sample die itself.
Compaction of the powder samples into tablets may reduce the sampling error because the samples
are in compacted form and handling of the loose powder samples by the operator or the analyst is
Several major pharmaceutical companies have already successfully utilized this technique in situations
where the blend samples were failing the content uniformity test while the tablets compressed from the
same blends were passing the test. This technique is strongly recommended especially when you